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W Fraser Symmans Selected Research

Residual Neoplasm

1/2022Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients.
1/2022Association of Residual Cancer Burden After Neoadjuvant Therapy and Event-Free Survival in Breast Cancer-Reply.
11/2021Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer: An Analysis of Data From the I-SPY2 Randomized Clinical Trial.
4/2017Long-Term Prognostic Risk After Neoadjuvant Chemotherapy Associated With Residual Cancer Burden and Breast Cancer Subtype.
7/2016Adaptive Randomization of Neratinib in Early Breast Cancer.
7/2015Reproducibility of residual cancer burden for prognostic assessment of breast cancer after neoadjuvant chemotherapy.
5/2013Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer.
2/2012Gene expression, molecular class changes, and pathway analysis after neoadjuvant systemic therapy for breast cancer.
1/2008PIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancer.
7/2007Thirty-gene pharmacogenomic test correlates with residual cancer burden after preoperative chemotherapy for breast cancer.
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W Fraser Symmans Research Topics

Disease

118Breast Neoplasms (Breast Cancer)
01/2022 - 05/2002
87Neoplasms (Cancer)
01/2022 - 08/2002
30Pathologic Complete Response
12/2021 - 06/2005
17Triple Negative Breast Neoplasms
12/2021 - 03/2008
14Residual Neoplasm
01/2022 - 04/2004
9Neoplasm Metastasis (Metastasis)
01/2021 - 05/2002
4Noninfiltrating Intraductal Carcinoma (DCIS)
01/2020 - 01/2006
3Inflammatory Breast Neoplasms
01/2021 - 02/2011
2Neutropenia
01/2018 - 01/2013
2Carcinoma (Carcinomatosis)
09/2015 - 04/2004
2Carcinogenesis
11/2009 - 01/2009
1Genomic Instability
11/2021
1Neoplasm Micrometastasis
09/2020
1Fatigue
01/2018
1Febrile Neutropenia
01/2018

Drug/Important Bio-Agent (IBA)

27Estrogen ReceptorsIBA
01/2020 - 02/2004
19Paclitaxel (Taxol)FDA LinkGeneric
12/2021 - 04/2004
16Hormones (Hormone)IBA
01/2022 - 09/2003
16Doxorubicin (Adriamycin)FDA LinkGeneric
11/2021 - 01/2003
15Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2021 - 04/2003
14Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2003
12Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2003
11AnthracyclinesIBA
01/2021 - 04/2004
10Fluorouracil (Carac)FDA LinkGeneric
11/2010 - 04/2003
9RNA (Ribonucleic Acid)IBA
11/2021 - 10/2002
9Trastuzumab (Herceptin)FDA Link
11/2021 - 01/2003
9Messenger RNA (mRNA)IBA
02/2021 - 03/2004
8Pharmaceutical PreparationsIBA
01/2022 - 07/2004
8ParaffinIBA
02/2021 - 01/2003
8Biological ProductsIBA
01/2021 - 08/2003
8taxaneIBA
01/2021 - 04/2007
8TamoxifenFDA LinkGeneric
01/2021 - 04/2007
7Carboplatin (JM8)FDA LinkGeneric
11/2021 - 07/2016
7Estrogens (Estrogen)FDA Link
01/2021 - 07/2003
7human ERBB2 proteinIBA
01/2021 - 03/2008
6Formaldehyde (Formol)FDA Link
02/2021 - 02/2004
6ErbB Receptors (EGF Receptor)IBA
01/2020 - 04/2004
6DNA (Deoxyribonucleic Acid)IBA
04/2014 - 01/2008
5Progesterone Receptors (Progesterone Receptor)IBA
01/2020 - 03/2008
4Poly(ADP-ribose) Polymerase InhibitorsIBA
12/2021 - 05/2014
4Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2020 - 01/2008
4Docetaxel (Taxotere)FDA Link
01/2019 - 01/2003
3veliparibIBA
11/2021 - 07/2016
3pertuzumabIBA
11/2021 - 01/2018
3Ado-Trastuzumab EmtansineIBA
11/2021 - 01/2018
3Phenobarbital (Luminal)FDA Link
05/2019 - 08/2005
3Taxoids (Taxanes)IBA
01/2013 - 12/2008
3Complementary DNA (cDNA)IBA
01/2006 - 03/2003
3Peptide Hydrolases (Proteases)FDA Link
03/2004 - 03/2003
2Aromatase InhibitorsIBA
01/2022 - 01/2021
2Androgen Receptors (Androgen Receptor)IBA
01/2021 - 05/2019
2TOR Serine-Threonine KinasesIBA
01/2020 - 05/2014
2Dasatinib (BMS 354825)FDA Link
10/2014 - 05/2010
2Phosphotransferases (Kinase)IBA
05/2014 - 11/2010
2Imatinib Mesylate (Gleevec)FDA Link
05/2014 - 10/2004
2Investigational DrugsIBA
05/2014 - 07/2012
2Small Interfering RNA (siRNA)IBA
04/2014 - 11/2010
2Monoclonal AntibodiesIBA
11/2009 - 04/2004
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
04/2009 - 04/2004
2Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
04/2007 - 06/2005
2Epirubicin (Ellence)FDA LinkGeneric
01/2007 - 06/2005
2Hematoxylin (Haematoxylon)IBA
04/2004 - 08/2002
2Eosine Yellowish-(YS) (Eosin)IBA
04/2004 - 08/2002
2EnzymesIBA
04/2004 - 01/2003
2Telomerase (Telomerase Reverse Transcriptase)IBA
03/2004 - 09/2003
2Cell Adhesion MoleculesIBA
03/2004 - 09/2003
2Transcription Factors (Transcription Factor)IBA
03/2004 - 09/2003
1Epidermal Growth Factor (EGF)IBA
01/2022
1PhosphoproteinsIBA
01/2022
1Immune Checkpoint InhibitorsIBA
12/2021
1olaparibIBA
12/2021
1durvalumabIBA
12/2021
1PlatinumIBA
11/2021
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
02/2021
1Estrogen Receptor Modulators (Antiestrogen)IBA
01/2021
1Folate Receptor 1IBA
01/2021
1Immunoconjugates (Immunoconjugate)IBA
01/2021
1mirvetuximab soravtansineIBA
01/2021
1Estrogen Receptor alphaIBA
01/2021
1Aurora Kinase AIBA
01/2021
1Dihydrotestosterone (Androstanolone)IBA
01/2021
1Estradiol (Delestrogen)FDA LinkGeneric
01/2021
1ProgesteroneFDA LinkGeneric
01/2021
1MK 2206IBA
01/2020
1pembrolizumabIBA
01/2020
1Alanine Transaminase (SGPT)IBA
01/2018
1Cytochrome P-450 CYP2D6 (CYP2D6)IBA
01/2018
1Cytochrome P-450 CYP2D6 InhibitorsIBA
01/2018
14-hydroxy-N-desmethyltamoxifenIBA
01/2018
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2018

Therapy/Procedure

49Therapeutics
01/2022 - 01/2003
44Neoadjuvant Therapy
01/2022 - 11/2002
42Drug Therapy (Chemotherapy)
11/2021 - 08/2002
5Aftercare (After-Treatment)
01/2018 - 11/2002
4Adjuvant Chemotherapy
01/2020 - 05/2004
4Segmental Mastectomy (Lumpectomy)
05/2012 - 09/2006
3Combination Drug Therapy (Combination Chemotherapy)
01/2012 - 01/2010
2Lymph Node Excision (Lymph Node Dissection)
09/2020 - 10/2013
2Precision Medicine
04/2009 - 11/2006
1Investigational Therapies (Experimental Therapy)
11/2021